Can artificial intelligence help cut emissions of greenhouse gases? In this second edition of the Artificial Intelligence for Climate Change Mitigation Roadmap, a team of 25 co-authors led by CGEP Inaugural Fellow David Sandalow explores that question, finding that AI has the potential to make significant contributions to fighting climate change. The Roadmap’s 17 chapters provide introductions to AI and climate change, examine the potential for AI to help reduce greenhouse gas emissions in eight sectors and discuss cross-cutting topics such as large language models and government policy. Each chapter includes 5-10 specific, actionable recommendations for realizing AI’s potential to help fight climate change.